- Mark Bernard Hardin was reared to the age of sixteen in Washington, D.C., and in 1854 entered the Virginia Military Institute, from which he was graduated in 1858. Immediately after his graduation he was appointed an assistant professor in this institution and in 1860 was appointed adjunct professor, in which capacity he continued to act until the beginning of the war. During his connection with this institution in the ante-bellum days he was intimately associated with General "Stonewall" Jackson, both as his student and as his co-professor. A warm friendship sprung up between the two; and this relation continued until the death of that gallant chieftain in 1863. (The Oconeean, Volume Two, 1904, page 6).
- September: The Blue Ridge Railroad is the first rail line to reach the Pendleton District and Fort Hill area, in September 1860. The Blue Ridge company constructs a 44.2 mile line between Belton and West Union, South Carolina via Anderson, Pendleton and the future site of Seneca. Its closest stop to Fort Hill is Cherry's Crossing, where the line crosses the Seneca River.
- December 24: The Declaration of the Immediate Causes Which Induce and Justify the Secession of South Carolina from the Federal Union, a legal proclamation, is issued this date by the government of South Carolina, explaining its reasons for seceding from the United States. The actual ordinance of secession had been issued on December 20. The declaration was written by Christopher Memminger.
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