- November 1: Future member of the first Clemson Board of Trustees, Daniel Keating Norris is born in Lower St. Matthews, Orangeburg County, South Carolina.
- December 8: Henry A. Clemson, an officer in the United States Navy in the early 1800s, born in 1820, is lost with his ship this date. A native of New Jersey, Clemson was appointed a midshipman in 1836. He served on the USS St. Mary's and the USS Somers during the Mexican-American War. He was lost when the USS Somers capsizes off Vera Cruz while chasing a blockade runner. The USS Clemson will be named for him.
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