- 1907: In an April Fools Day prank, the first Pendleton Guards constitutes itself in front of the Main Building and plays hooky from classes, marching off to Pendleton where they loll around the square. The administration is not amused and warns the cadets never again to engage in mass cutting of classes. Being students, they will of course, repeat the march the following year, with much more severe repercussions!
- 1908: In a poorly thought out April Fool's Day prank, over three hundred cadets from the "Pendleton Guards" march to Pendleton, returning with a cannon they dismount from the town square. President Patrick Hues Mell expels the entire group, gutting the football team, as several members had participated in the ill-advised roadtrip. Many are re-admitted the following year.
- 1946: The Tiger ("The World's Most Uninteresting College Rag") publishes April Fools' issue (Volume XXXIX, Number 32a) - headlined "Shorty Is New President" with sub-head "Oscar is found dead in Latrine".
- 1960: WSBF makes its first over-the-air broadcast.
- 1974: Comedian and musician Martin Mull and His Fabulous Furniture appears in a free concert in Tillman Auditorium.
- 1980: Jazz guitarist Larry Coryell appears in the Clemson House Ballroom.
- 1986: James L. Lucas, III, Class of 1973, Tiger band grad student member who produced the 1974 edition of The Unhymnal, dies of a heart attack, age 34.
- 1987: Women's basketball Coach Jim Davis is hired.
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