- 1888 - Thomas Green Clemson dies. His will established Clemson Agricultural College of South Carolina.
- 1899 - Baseball coach and assistant football coach and instructor in forge and foundry, R.T.V. Bowman dies. Bowman Field is named for him.
- 1970 - The R.L. Bryan Company in Columbia refuses to print The Chronicle's Spring 1970 issue, Vol. X, No. 11, over objections to an "obscene" passage in the text.
- 1973 - First annual Bengal Ball is held by the Union at Y Beach.
- 1977: Varsity cheerleaders for 1977-1978 are selected. They are Fulton Breen, Chris Carter, Joey Erwin, Terry Hall, Steve Klengson, Jim Mehserle, Colin Richmond, Aline Crews, Alice Gorena, Mary Hill, Cathy Pool, Jan Rushton and Kathy Watts. Head cheerleader is George Langstaff, and the Tiger is Randall Addison. J.V. cheerleaders are Joe Barna, Thom Brown, Red Cook, Clark Curry, Steve Deconti, Bill Newell, Tony Pichirallo, Steve Trotman, Mary Barnes, Carol Corley, Cindy McDowell, Lynn Peck, Robin Russell and Julie Stephens. The J.V. Tiger is Dave Rheney. (TAPS 1978, Volume 68, page 365.)
- 1978 - Seventeen Democratic candidates seeking statewide office converge on the Clemson campus, sponsored by the Clemson Young Democrats, and speak to a crowd of about 250 students on the Union Plaza. Senate candidate Charles "Pug" Ravenel, and gubernatorial candidates Richard "Dick" Riley and Tom Turnipseed lead off stump speeches.
- 1978 - Three bartenders at the Bookstore are arrested for selling alcoholic beverages to minors while police officers accompanied by an Alcoholic Beverage Control officer are present.
- Early April, 1979: A team of investigators from the Office of Civil Rights, Department of Health, Education and Welfare, visit the campus to review compliance with Title XI of the 1964 Civil Rights Act.
- 1992 - First issue of The Clemson Spectator, which later becomes The Tiger Town Observer, is published.
- 2000 - The Hendrix Center is completed.
- 2001 - Former Football Coach Charlie Pell honored at halftime at the Orange and White game for his part in putting Clemson back on a winning track.
- 2006: Tiger Tails changes ownership and reopens as Static exotic nightclub for men and women. Kay Wall replaces Joseph Boykin as Dean of Libraries.
- 2007: Big Dave's BBQ opens at 1060 Tiger Boulevard, Clemson.
- 2008: Food Lion opens new store at 107 Canoy Lane, Clemson. Tiger Card accepted.