- February 17: Columbia burns down.
- March 19-March 21: Future Clemson Board of Trustees member, D. K. Norris, serving in Company F, Second Regiment, S.C. Heavy Artillery, rank of Private, is badly wounded at the Battle of Bentonville, North Carolina, fought these dates.
- March 25: Augustus Schilletter born. (http://files.usgwarchives.net/sc/oconee/cemeteries/c243a.txt)
- April 9: Robert Esli Bowen, future Life Trustee for Clemson Agricultural College, is present at Appomattox Court House, Virginia, as a Confederate soldier, for the surrender of the Army of Northern Virginia.
- May 29: President Andrew Johnson issues a proclamation extending pardons to ex-Confederates who take the oath to support the Constitution and the Union. However, prominent ex-Confederate officials and persons of wealth are not included in this general pardon. These persons must apply to the President individually if they desire amnesty. (Lander, Jr., Ernest McPherson, "A History of South Carolina, 1865-1960", The University of North Carolina Press, Chapel Hill, 1960, pages 6-7.)
- June 2: Bessie Brandon Craig, future wife of Richard Newman Brackett, is born in Cabanass County, North Carolina.
- June 9: Thomas Green Clemson is paroled at Shreveport, Louisiana, after serving four years in the Army of the Trans-Mississippi, CSA, during which time he worked in Arkansas and Texas developing nitrate mines for explosives.
- July 3: Major Mark Bernard Hardin, CSA, Clemson's first Professor of Chemistry, is released as a Confederate prisoner of war from Johnson's Island, Lake Erie.
- Major Mark Bernard Hardin takes a job in New York City as an analytical chemist for two years after the close of the war, until returning to the Virginia Military Institute as full Professor of Chemistry in 1867, which position he held until 1890.
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