- January 2: Clemson meets the sixth-ranked Tennessee Volunteers in the Chick-fil-A Peach Bowl in the Georgia Dome in Atlanta, winning, 27-14, for a season outcome of 9-4, 5-3 in the ACC for third place in conference. The Tigers are ranked twenty-second in both the Associated Press and USA Today final polls.
- February 7: The Washington Post runs a story on page A-1 about the pending demise of all of Manifest Record's locations, including the store on College Avenue, headlined "Requiem for the Record Store - Downloaders and Discounters Are Driving Out Music Retailers". Owner Carl Singmaster is quoted on the loss of revenue in the internet age, a 30 percent drop over three years, and virtually all of the Clemson outlet's trade when the University wired the dormitories for highspeed internet access.
- February 25: The University Ridge apartment complex is destroyed in a fire.
- March 4: Country duo Brooks and Dunn perform in Littlejohn Coliseum.
- Spring: A new speech and communications lab is added to Daniel Hall.
- April: Feet First opens in Rubin Square.
- April 17: Country legend, Alabama, performs in Littlejohn Coliseum.
- July 1: The Atlantic Coast Conference expands to 11 members, with the addition of the University of Miami and Virginia Polytechnic Institute & State University.
- July 21: Two USMC F/A-18 Hornets of VMFA-134, 3rd Marine Air Wing, based at MCAS Miramar, California, suffer mid-air collision over the Columbia River, 120 miles E of Portland, Oregon, shortly after 1430 hrs., killing Marine Reservists Maj. Gary R. Fullerton, 36, of Spartanburg, South Carolina and a 1990 graduate of Clemson University, and Capt. Jeffrey L. Ross, 36, of Old Hickory, Tennessee in F/A-18B, BuNo 162870, 'MF-00', coming down in the river. Maj. Craig Barden, 38, ejects from F/A-18A, BuNo 163097, 'MF-04', landing nearby on a hillside W of Arlington, Oregon, and is taken to Mid-Columbia Medical Center in The Dalles, suffering minor injuries. All three crew eject but only two parachutes open. The fighters were on their way to the Boardman Air Force Range, where the Oregon Air National Guard trains, when they collided, said one spokesman. Another spokesman told the Associated Press that the planes were on a low-altitude training exercise.
- Fall: Renovation of McAdams Hall completed.
- September: Flagpole erected at the Esso Club.
- September 4: The fifteenth-ranked Tigers defeat Wake Forest, 37-30, in two overtimes, in Death Valley.
- September 11: Ranked twentieth, Clemson travels to Georgia Tech for night game, losing, 24-28.
- September 18: The Tigers travel to Texas A&M, lose night game, 6-27.
- September 25: Bowden Bowl VI - The eighth-ranked Seminoles beat the Tigers 41-22 in Tallahassee, in the only father-son coaching series in college football history.
- October 7: Clemson plays tenth-ranked Virginia in Charlottesville night game, losing, 10-30.
- October 16: Tigers host Utah State, winning, 35-6.
- Fall: Kaye Herth begins her tenure as Director of the School of Nursing. She follows Barbara Logan, who was the School's first director after University restructuring created the official School of Nursing, and Rosanne Pruitt, who served as interim.
- Fall: The Hardee's restaurant on Walter Cox Boulevard which opened in 1975 closes for eventual redevelopment of the site into condominiums.
- Fall: Mock Turtle Soup presents the 1st annual 24 Hour Improv-a-thon, benefitting Habitat for Humanity, during Homecoming.
- Beezers opens on College Avenue.
- October 23: Clemson hosts Maryland, winning, 10-7.
- October 30: The Tigers beat N.C. State in Memorial Stadium, 26-20.
- November 6: The Tigers play at eleventh-ranked Miami (Florida) in night game, winning, 24-17, in overtime.
- November 13: Clemson loses at Duke, 13-16.
- November 20: Clemson defeats the University of South Carolina in Death Valley, 29-7, but ugly melee breaks out between the teams late in the fourth quarter, requiring coaches and state troopers to get involved to quell the mayhem. Both schools are bowl eligible, but both schools announce they will not accept bowl bids, as self punishment for unacceptable behavior at the final game. This is the Tigers' 600th victory, and the team ends the season with a 6-5 record, 4-4 in the ACC for sixth place in conference. This is also Lou Holtz's final game as head coach of the Gamecocks. http://www.youtube.com/watch?v=bDzl1dJthYo&feature=related